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Spin state dependent peroxidase activity of heme bound amyloid β peptides relevant to Alzheimer's disease
The colocalization of heme rich deposits in the senile plaque of Aβ in the cerebral cortex of the Alzheimer's disease (AD) brain along with altered heme homeostasis and heme deficiency symptoms in AD patients has invoked the association of heme in AD pathology. Heme bound Aβ complexes, dependin...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9749105/ https://www.ncbi.nlm.nih.gov/pubmed/36545147 http://dx.doi.org/10.1039/d2sc05008k |