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Spin state dependent peroxidase activity of heme bound amyloid β peptides relevant to Alzheimer's disease

The colocalization of heme rich deposits in the senile plaque of Aβ in the cerebral cortex of the Alzheimer's disease (AD) brain along with altered heme homeostasis and heme deficiency symptoms in AD patients has invoked the association of heme in AD pathology. Heme bound Aβ complexes, dependin...

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Detalles Bibliográficos
Autores principales: Nath, Arnab Kumar, Roy, Madhuparna, Dey, Chinmay, Dey, Abhishek, Dey, Somdatta Ghosh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9749105/
https://www.ncbi.nlm.nih.gov/pubmed/36545147
http://dx.doi.org/10.1039/d2sc05008k