Cargando…

Selective editing of a peptide skeleton via C–N bond formation at N-terminal aliphatic side chains

The applications of peptides and peptidomimetics have been demonstrated in the fields of therapeutics, diagnostics, and chemical biology. Strategies for the direct late-stage modification of peptides and peptidomimetics are highly desirable in modern drug discovery. Transition-metal-catalyzed C–H fu...

Descripción completa

Detalles Bibliográficos
Autores principales: Han, Yujie, Shi, Junjie, Li, Songrong, Dan, Tingting, Yang, Wenwen, Yang, Mingyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9749142/
https://www.ncbi.nlm.nih.gov/pubmed/36545141
http://dx.doi.org/10.1039/d2sc04909k