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Species-specific basecallers improve actual accuracy of nanopore sequencing in plants

BACKGROUND: Long-read sequencing platforms offered by Oxford Nanopore Technologies (ONT) allow native DNA containing epigenetic modifications to be directly sequenced, but can be limited by lower per-base accuracies. A key step post-sequencing is basecalling, the process of converting raw electrical...

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Detalles Bibliográficos
Autores principales: Ferguson, Scott, McLay, Todd, Andrew, Rose L., Bruhl, Jeremy J., Schwessinger, Benjamin, Borevitz, Justin, Jones, Ashley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9749173/
https://www.ncbi.nlm.nih.gov/pubmed/36517904
http://dx.doi.org/10.1186/s13007-022-00971-2