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Granulovacuolar degeneration bodies are independently induced by tau and α-synuclein pathology
BACKGROUND: Granulovacuolar degeneration bodies (GVBs) are intracellular vesicular structures that commonly accompany pathological tau accumulations in neurons of patients with tauopathies. Recently, we developed the first model for GVBs in primary neurons, that requires exogenous tau seeds to elici...
Autores principales: | Jorge-Oliva, Marta, Smits, Jasper F. M., Wiersma, Vera I., Hoozemans, Jeroen J. M., Scheper, Wiep |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9749177/ https://www.ncbi.nlm.nih.gov/pubmed/36517915 http://dx.doi.org/10.1186/s13195-022-01128-y |
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