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Combination of IL-17A/F and TNF-α uniquely alters the bronchial epithelial cell proteome to enhance proteins that augment neutrophil migration

BACKGROUND: The heterodimer interleukin (IL)-17A/F is elevated in the lungs in chronic respiratory disease such as severe asthma, along with the pro-inflammatory cytokine tumor necrosis factor-α (TNF-α). Although IL-17A/F and TNF-α are known to functionally cooperate to exacerbate airway inflammatio...

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Detalles Bibliográficos
Autores principales: Altieri, Anthony, Piyadasa, Hadeesha, Hemshekhar, Mahadevappa, Osawa, Natasha, Recksiedler, Breann, Spicer, Victor, Hiemstra, Pieter S, Halayko, Andrew J, Mookherjee, Neeloffer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9749191/
https://www.ncbi.nlm.nih.gov/pubmed/36517803
http://dx.doi.org/10.1186/s12950-022-00323-w