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Combination of IL-17A/F and TNF-α uniquely alters the bronchial epithelial cell proteome to enhance proteins that augment neutrophil migration
BACKGROUND: The heterodimer interleukin (IL)-17A/F is elevated in the lungs in chronic respiratory disease such as severe asthma, along with the pro-inflammatory cytokine tumor necrosis factor-α (TNF-α). Although IL-17A/F and TNF-α are known to functionally cooperate to exacerbate airway inflammatio...
Autores principales: | Altieri, Anthony, Piyadasa, Hadeesha, Hemshekhar, Mahadevappa, Osawa, Natasha, Recksiedler, Breann, Spicer, Victor, Hiemstra, Pieter S, Halayko, Andrew J, Mookherjee, Neeloffer |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9749191/ https://www.ncbi.nlm.nih.gov/pubmed/36517803 http://dx.doi.org/10.1186/s12950-022-00323-w |
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