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Ceramide induces pyroptosis through TXNIP/NLRP3/GSDMD pathway in HUVECs

BACKGROUND: Pyroptosis of endothelial cells is a new cause of endothelial dysfunction in multiple diseases. Ceramide acts as a potential bioactive mediator of inflammation and increases vascular endothelial permeability in many diseases, whether it can aggravate vascular endothelial injury by induci...

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Detalles Bibliográficos
Autores principales: Liu, Fangfang, Zhang, Yangyang, Shi, Yining, Xiong, Kai, Wang, Fugui, Yang, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9749313/
https://www.ncbi.nlm.nih.gov/pubmed/36517743
http://dx.doi.org/10.1186/s12860-022-00459-w