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Ceramide induces pyroptosis through TXNIP/NLRP3/GSDMD pathway in HUVECs
BACKGROUND: Pyroptosis of endothelial cells is a new cause of endothelial dysfunction in multiple diseases. Ceramide acts as a potential bioactive mediator of inflammation and increases vascular endothelial permeability in many diseases, whether it can aggravate vascular endothelial injury by induci...
Autores principales: | Liu, Fangfang, Zhang, Yangyang, Shi, Yining, Xiong, Kai, Wang, Fugui, Yang, Jin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9749313/ https://www.ncbi.nlm.nih.gov/pubmed/36517743 http://dx.doi.org/10.1186/s12860-022-00459-w |
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