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Protein charge parameters that influence stability and cellular internalization of polyelectrolyte complex micelles
Proteins are an important class of biologics, but there are several recurring challenges to address when designing protein-based therapeutics. These challenges include: the propensity of proteins to aggregate during formulation, relatively low loading in traditional hydrophobic delivery vehicles, an...
Autores principales: | Kapelner, Rachel A., Fisher, Rachel S., Elbaum-Garfinkle, Shana, Obermeyer, Allie C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9749388/ https://www.ncbi.nlm.nih.gov/pubmed/36545145 http://dx.doi.org/10.1039/d2sc00192f |
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