Oxaliplatin disrupts nucleolar function through biophysical disintegration

Platinum (Pt) compounds such as oxaliplatin are among the most commonly prescribed anti-cancer drugs. Despite their considerable clinical impact, the molecular basis of platinum cytotoxicity and cancer specificity remain unclear. Here we show that oxaliplatin, a backbone for the treatment of colorec...

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Detalles Bibliográficos
Autores principales: Broder Schmidt, H., Jaafar, Zane A., Erik Wulff, B., Rodencal, Jason J., Hong, Kibeom, Aziz-Zanjani, Mohammad O., Jackson, Peter K., Leonetti, Manuel D., Dixon, Scott J., Rohatgi, Rajat, Brandman, Onn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9749789/
https://www.ncbi.nlm.nih.gov/pubmed/36351392
http://dx.doi.org/10.1016/j.celrep.2022.111629

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9749789/
https://www.ncbi.nlm.nih.gov/pubmed/36351392
http://dx.doi.org/10.1016/j.celrep.2022.111629

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