Defective synaptic plasticity in a model of Coffin–Lowry syndrome is rescued by simultaneously targeting PKA and MAPK pathways

Empirical and computational methods were combined to examine whether individual or dual-drug treatments can restore the deficit in long-term synaptic facilitation (LTF) of the Aplysia sensorimotor synapse observed in a cellular model of Coffin–Lowry syndrome (CLS). The model was produced by pharmaco...

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Detalles Bibliográficos
Autores principales: Liu, Rong-Yu, Zhang, Yili, Smolen, Paul, Cleary, Leonard J., Byrne, John H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9749851/
https://www.ncbi.nlm.nih.gov/pubmed/36446603
http://dx.doi.org/10.1101/lm.053625.122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9749851/
https://www.ncbi.nlm.nih.gov/pubmed/36446603
http://dx.doi.org/10.1101/lm.053625.122

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