2-hydroxyisobutyric acid (2-HIBA) modulates ageing and fat deposition in Caenorhabditis elegans

High levels of 2-hydroxyisobutyric acid (2-HIBA) were found in urines of patients with obesity and hepatic steatosis, suggesting a potential involvement of this metabolite in clinical conditions. The gut microbial origin of 2-HIBA was hypothesized, however its actual origin and role in biological pr...

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Detalles Bibliográficos
Autores principales: Schifano, Emily, Conta, Giorgia, Preziosi, Adele, Ferrante, Carino, Batignani, Giovanni, Mancini, Patrizia, Tomassini, Alberta, Sciubba, Fabio, Scopigno, Tullio, Uccelletti, Daniela, Miccheli, Alfredo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9749906/
https://www.ncbi.nlm.nih.gov/pubmed/36533081
http://dx.doi.org/10.3389/fmolb.2022.986022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9749906/
https://www.ncbi.nlm.nih.gov/pubmed/36533081
http://dx.doi.org/10.3389/fmolb.2022.986022

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