Sustained Low Relapse Rate With Highly Variable B-Cell Repopulation Dynamics With Extended Rituximab Dosing Intervals in Multiple Sclerosis

BACKGROUND AND OBJECTIVES: B cell–depleting therapies are highly effective in relapsing-remitting multiple sclerosis (RRMS) but are associated with increased infection risk and blunted humoral vaccination responses. Extension of dosing intervals may mitigate such negative effects, but its consequenc...

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Detalles Bibliográficos
Autores principales: Starvaggi Cucuzza, Chiara, Longinetti, Elisa, Ruffin, Nicolas, Evertsson, Björn, Kockum, Ingrid, Jagodic, Maja, Al Nimer, Faiez, Frisell, Thomas, Piehl, Fredrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9749930/
https://www.ncbi.nlm.nih.gov/pubmed/36411076
http://dx.doi.org/10.1212/NXI.0000000000200056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9749930/
https://www.ncbi.nlm.nih.gov/pubmed/36411076
http://dx.doi.org/10.1212/NXI.0000000000200056

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