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Sustained Low Relapse Rate With Highly Variable B-Cell Repopulation Dynamics With Extended Rituximab Dosing Intervals in Multiple Sclerosis
BACKGROUND AND OBJECTIVES: B cell–depleting therapies are highly effective in relapsing-remitting multiple sclerosis (RRMS) but are associated with increased infection risk and blunted humoral vaccination responses. Extension of dosing intervals may mitigate such negative effects, but its consequenc...
Autores principales: | Starvaggi Cucuzza, Chiara, Longinetti, Elisa, Ruffin, Nicolas, Evertsson, Björn, Kockum, Ingrid, Jagodic, Maja, Al Nimer, Faiez, Frisell, Thomas, Piehl, Fredrik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9749930/ https://www.ncbi.nlm.nih.gov/pubmed/36411076 http://dx.doi.org/10.1212/NXI.0000000000200056 |
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