LOF variants identifying candidate genes of laterality defects patients with congenital heart disease

Defects in laterality pattern can result in abnormal positioning of the internal organs during the early stages of embryogenesis, as manifested in heterotaxy syndrome and situs inversus, while laterality defects account for 3~7% of all congenital heart defects (CHDs). However, the pathogenic mechani...

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Detalles Bibliográficos
Autores principales: Liu, Sijie, Wei, Wei, Wang, Pengcheng, Liu, Chunjie, Jiang, Xuechao, Li, Tingting, Li, Fen, Wu, Yurong, Chen, Sun, Sun, Kun, Xu, Rang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9749982/
https://www.ncbi.nlm.nih.gov/pubmed/36459505
http://dx.doi.org/10.1371/journal.pgen.1010530

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9749982/
https://www.ncbi.nlm.nih.gov/pubmed/36459505
http://dx.doi.org/10.1371/journal.pgen.1010530

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