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DREAMM: a web-based server for drugging protein-membrane interfaces as a novel workflow for targeted drug design

SUMMARY: The allosteric modulation of peripheral membrane proteins (PMPs) by targeting protein-membrane interactions with drug-like molecules represents a new promising therapeutic strategy for proteins currently considered undruggable. However, the accessibility of protein-membrane interfaces by sm...

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Detalles Bibliográficos
Autores principales: Chatzigoulas, Alexios, Cournia, Zoe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9750117/
https://www.ncbi.nlm.nih.gov/pubmed/36355565
http://dx.doi.org/10.1093/bioinformatics/btac680