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DREAMM: a web-based server for drugging protein-membrane interfaces as a novel workflow for targeted drug design
SUMMARY: The allosteric modulation of peripheral membrane proteins (PMPs) by targeting protein-membrane interactions with drug-like molecules represents a new promising therapeutic strategy for proteins currently considered undruggable. However, the accessibility of protein-membrane interfaces by sm...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9750117/ https://www.ncbi.nlm.nih.gov/pubmed/36355565 http://dx.doi.org/10.1093/bioinformatics/btac680 |