3DPolyS-LE: an accessible simulation framework to model the interplay between chromatin and loop extrusion

SUMMARY: Recent studies suggest that the loop extrusion activity of Structural Maintenance of Chromosomes complexes is central to proper organization of genomes in vivo. Polymer physics-based modeling of chromosome structure has been instrumental to assess which structures such extrusion can create....

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Detalles Bibliográficos
Autores principales: Gitchev, Todor, Zala, Gabriel, Meister, Peter, Jost, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Applications Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9750120/
https://www.ncbi.nlm.nih.gov/pubmed/36355469
http://dx.doi.org/10.1093/bioinformatics/btac705

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9750120/
https://www.ncbi.nlm.nih.gov/pubmed/36355469
http://dx.doi.org/10.1093/bioinformatics/btac705

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