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3DPolyS-LE: an accessible simulation framework to model the interplay between chromatin and loop extrusion
SUMMARY: Recent studies suggest that the loop extrusion activity of Structural Maintenance of Chromosomes complexes is central to proper organization of genomes in vivo. Polymer physics-based modeling of chromosome structure has been instrumental to assess which structures such extrusion can create....
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9750120/ https://www.ncbi.nlm.nih.gov/pubmed/36355469 http://dx.doi.org/10.1093/bioinformatics/btac705 |