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HaploDMF: viral haplotype reconstruction from long reads via deep matrix factorization

MOTIVATION: Lacking strict proofreading mechanisms, many RNA viruses can generate progeny with slightly changed genomes. Being able to characterize highly similar genomes (i.e. haplotypes) in one virus population helps study the viruses’ evolution and their interactions with the host/other microbes....

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Detalles Bibliográficos
Autores principales: Cai, Dehan, Shang, Jiayu, Sun, Yanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9750122/
https://www.ncbi.nlm.nih.gov/pubmed/36308467
http://dx.doi.org/10.1093/bioinformatics/btac708