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HaploDMF: viral haplotype reconstruction from long reads via deep matrix factorization
MOTIVATION: Lacking strict proofreading mechanisms, many RNA viruses can generate progeny with slightly changed genomes. Being able to characterize highly similar genomes (i.e. haplotypes) in one virus population helps study the viruses’ evolution and their interactions with the host/other microbes....
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9750122/ https://www.ncbi.nlm.nih.gov/pubmed/36308467 http://dx.doi.org/10.1093/bioinformatics/btac708 |