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A universal influenza mRNA vaccine candidate boosts T cell responses and reduces zoonotic influenza virus disease in ferrets

Universal influenza vaccines should protect against continuously evolving and newly emerging influenza viruses. T cells may be an essential target of such vaccines, as they can clear infected cells through recognition of conserved influenza virus epitopes. We evaluated a novel T cell–inducing nucleo...

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Detalles Bibliográficos
Autores principales: van de Ven, Koen, Lanfermeijer, Josien, van Dijken, Harry, Muramatsu, Hiromi, Vilas Boas de Melo, Caroline, Lenz, Stefanie, Peters, Florence, Beattie, Mitchell B., Lin, Paulo J. C., Ferreira, José A., van den Brand, Judith, van Baarle, Debbie, Pardi, Norbert, de Jonge, Jørgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9750153/
https://www.ncbi.nlm.nih.gov/pubmed/36516261
http://dx.doi.org/10.1126/sciadv.adc9937