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Arf GTPase activates the WAVE regulatory complex through a distinct binding site

Cross-talk between Rho- and Arf-family guanosine triphosphatases (GTPases) plays an important role in linking the actin cytoskeleton to membrane protrusions, organelle morphology, and vesicle trafficking. The central actin regulator, WAVE regulatory complex (WRC), integrates Rac1 (a Rho-family GTPas...

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Detalles Bibliográficos
Autores principales: Yang, Sheng, Tang, Yubo, Liu, Yijun, Brown, Abbigale J., Schaks, Matthias, Ding, Bojian, Kramer, Daniel A., Mietkowska, Magdalena, Ding, Li, Alekhina, Olga, Billadeau, Daniel D., Chowdhury, Saikat, Wang, Junmei, Rottner, Klemens, Chen, Baoyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9750158/
https://www.ncbi.nlm.nih.gov/pubmed/36516255
http://dx.doi.org/10.1126/sciadv.add1412