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VASH1–SVBP and VASH2–SVBP generate different detyrosination profiles on microtubules

The detyrosination/tyrosination cycle of α-tubulin is critical for proper cell functioning. VASH1–SVBP and VASH2–SVBP are ubiquitous enzymes involved in microtubule detyrosination, whose mode of action is little known. Here, we show in reconstituted systems and cells that VASH1–SVBP and VASH2–SVBP d...

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Detalles Bibliográficos
Autores principales: Ramirez-Rios, Sacnicte, Choi, Sung Ryul, Sanyal, Chadni, Blum, Thorsten B., Bosc, Christophe, Krichen, Fatma, Denarier, Eric, Soleilhac, Jean-Marc, Blot, Béatrice, Janke, Carsten, Stoppin-Mellet, Virginie, Magiera, Maria M., Arnal, Isabelle, Steinmetz, Michel O., Moutin, Marie-Jo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9750192/
https://www.ncbi.nlm.nih.gov/pubmed/36512346
http://dx.doi.org/10.1083/jcb.202205096