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VASH1–SVBP and VASH2–SVBP generate different detyrosination profiles on microtubules
The detyrosination/tyrosination cycle of α-tubulin is critical for proper cell functioning. VASH1–SVBP and VASH2–SVBP are ubiquitous enzymes involved in microtubule detyrosination, whose mode of action is little known. Here, we show in reconstituted systems and cells that VASH1–SVBP and VASH2–SVBP d...
Autores principales: | Ramirez-Rios, Sacnicte, Choi, Sung Ryul, Sanyal, Chadni, Blum, Thorsten B., Bosc, Christophe, Krichen, Fatma, Denarier, Eric, Soleilhac, Jean-Marc, Blot, Béatrice, Janke, Carsten, Stoppin-Mellet, Virginie, Magiera, Maria M., Arnal, Isabelle, Steinmetz, Michel O., Moutin, Marie-Jo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9750192/ https://www.ncbi.nlm.nih.gov/pubmed/36512346 http://dx.doi.org/10.1083/jcb.202205096 |
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