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Mechanisms of differential desensitization of metabotropic glutamate receptors

G protein-coupled receptors (GPCRs) interact with intracellular transducers to control both signal initiation and desensitization, but the distinct mechanisms that control the regulation of different GPCR subtypes are unclear. Here we use fluorescence imaging and electrophysiology to examine the met...

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Detalles Bibliográficos
Autores principales: Abreu, Nohely, Acosta-Ruiz, Amanda, Xiang, Guoqing, Levitz, Joshua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9750234/
https://www.ncbi.nlm.nih.gov/pubmed/33910009
http://dx.doi.org/10.1016/j.celrep.2021.109050