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SARS-CoV-2 viral protein ORF3A injures renal tubules by interacting with TRIM59 to induce STAT3 activation

Acute kidney injury occurs frequently in COVID-19 patients infected by the coronavirus SARS-CoV-2, and infection of kidney cells by this virus has been reported. However, little is known about the direct impact of the SARS-CoV-2 infection upon the renal tubular cells. We report that SARS-CoV-2 activ...

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Detalles Bibliográficos
Autores principales: Cai, Hong, Chen, Ya, Feng, Ye, Asadi, Morad, Kaufman, Lewis, Lee, Kyung, Kehrer, Thomas, Miorin, Lisa, Garcia-Sastre, Adolfo, Gusella, G. Luca, Gu, Leyi, Ni, Zhaohui, Mou, Shan, He, John Cijiang, Zhou, Weibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9750503/
https://www.ncbi.nlm.nih.gov/pubmed/36523164
http://dx.doi.org/10.1016/j.ymthe.2022.12.008