Hypoxia Inhibits Osteogenesis and Promotes Adipogenesis of Fibroblast-like Synoviocytes via Upregulation of Leptin in Patients with Rheumatoid Arthritis

Hypoxia is associated with the pathogenesis of rheumatoid arthritis (RA). RA fibroblast-like synoviocytes (FLSs) are able to differentiate into osteoblasts and adipocytes. In this study, we aimed to investigate the role of hypoxia in the osteogenesis or adipogenesis of RA-FLSs. Bioinformatics analys...

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Detalles Bibliográficos
Autores principales: Ding, Menglei, Cheng, Yu, Xu, Zhen, Lu, Ying, Li, Jing, Lu, Liu, Zong, Ming, Fan, Lieying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9750767/
https://www.ncbi.nlm.nih.gov/pubmed/36530571
http://dx.doi.org/10.1155/2022/1431399

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9750767/
https://www.ncbi.nlm.nih.gov/pubmed/36530571
http://dx.doi.org/10.1155/2022/1431399

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