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Distinct clinicopathological characteristics, genomic alteration and prognosis in breast cancer with concurrent TP53 mutation and MYC amplification

BACKGROUND: Both TP53 mutation and MYC amplification indicate poor outcomes in breast cancer (BC), but the clinical values of concurrent TP53 and MYC alterations have not been well‐characterized. METHODS: A total of 494 BC patients diagnosed at Guangdong Provincial People's Hospital (GDPH) were...

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Detalles Bibliográficos
Autores principales: Lin, Xiaoyi, Lin, Xin, Guo, Lijuan, Wang, Yulei, Zhang, Guochun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9750818/
https://www.ncbi.nlm.nih.gov/pubmed/36305094
http://dx.doi.org/10.1111/1759-7714.14703