Gastrointestinal cancer-associated fibroblasts expressing Junctional Adhesion Molecule-A are amenable to infection by oncolytic reovirus

Gastrointestinal (GI) cancers are characterized by extensive tumor stroma that both promotes tumor progression and acts as a physical barrier for adjacent tumor cells, limiting the effect of current treatment modalities. Oncolytic virotherapy is currently investigated in clinical trials as a novel t...

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Detalles Bibliográficos
Autores principales: Harryvan, Tom J., Golo, Matteo, Dam, Nicole, Schoonderwoerd, Mark J. A., Farshadi, Elham Aida, Hornsveld, Marten, Hoeben, Rob C., Hawinkels, Lukas J. A. C., Kemp, Vera
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9750869/
https://www.ncbi.nlm.nih.gov/pubmed/35869278
http://dx.doi.org/10.1038/s41417-022-00507-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9750869/
https://www.ncbi.nlm.nih.gov/pubmed/35869278
http://dx.doi.org/10.1038/s41417-022-00507-9

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