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Gastrointestinal cancer-associated fibroblasts expressing Junctional Adhesion Molecule-A are amenable to infection by oncolytic reovirus

Gastrointestinal (GI) cancers are characterized by extensive tumor stroma that both promotes tumor progression and acts as a physical barrier for adjacent tumor cells, limiting the effect of current treatment modalities. Oncolytic virotherapy is currently investigated in clinical trials as a novel t...

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Detalles Bibliográficos
Autores principales:	Harryvan, Tom J., Golo, Matteo, Dam, Nicole, Schoonderwoerd, Mark J. A., Farshadi, Elham Aida, Hornsveld, Marten, Hoeben, Rob C., Hawinkels, Lukas J. A. C., Kemp, Vera
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group US 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9750869/ https://www.ncbi.nlm.nih.gov/pubmed/35869278 http://dx.doi.org/10.1038/s41417-022-00507-9

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