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Antisense oligonucleotides as a potential treatment for brain deficits observed in myotonic dystrophy type 1

Myotonic dystrophy, or dystrophia myotonica type 1 (DM1), is a multi-systemic disorder and is the most common adult form of muscular dystrophy. It affects not only muscles but also many organs, including the brain. Cerebral impairments include cognitive deficits, daytime sleepiness, and loss of visu...

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Detalles Bibliográficos
Autores principales: Ait Benichou, Siham, Jauvin, Dominic, De Serres-Bérard, Thiéry, Pierre, Marion, Ling, Karen K., Bennett, C. Frank, Rigo, Frank, Gourdon, Genevieve, Chahine, Mohamed, Puymirat, Jack
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9750879/
https://www.ncbi.nlm.nih.gov/pubmed/35075265
http://dx.doi.org/10.1038/s41434-022-00316-7