Activation of Disulfide Redox Switch in REDD1 Promotes Oxidative Stress Under Hyperglycemic Conditions

The stress response protein regulated in development and DNA damage response 1 (REDD1) has been implicated in visual deficits in patients with diabetes. The aim here was to investigate the mechanism responsible for the increase in retinal REDD1 protein content that is observed with diabetes. We foun...

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Detalles Bibliográficos
Autores principales: Miller, William P., Sha, Congzhou M., Sunilkumar, Siddharth, Toro, Allyson L., VanCleave, Ashley M., Kimball, Scot R., Dokholyan, Nikolay V., Dennis, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2022
Materias:
Complications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9750946/
https://www.ncbi.nlm.nih.gov/pubmed/36170669
http://dx.doi.org/10.2337/db22-0355

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9750946/
https://www.ncbi.nlm.nih.gov/pubmed/36170669
http://dx.doi.org/10.2337/db22-0355

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