Structure-based lead optimization of peptide-based vinyl methyl ketones as SARS-CoV-2 main protease inhibitors

Despite several major achievements in the development of vaccines and antivirals, the fight against SARS-CoV-2 and the health problems accompanying COVID-19 are still ongoing. SARS-CoV-2 main protease (M(pro)), an essential viral cysteine protease, is a crucial target for the development of antivira...

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Detalles Bibliográficos
Autores principales: Previti, Santo, Ettari, Roberta, Calcaterra, Elsa, Di Maro, Salvatore, Hammerschmidt, Stefan J., Müller, Christin, Ziebuhr, John, Schirmeister, Tanja, Cosconati, Sandro, Zappalà, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Masson SAS. 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9751013/
https://www.ncbi.nlm.nih.gov/pubmed/36549112
http://dx.doi.org/10.1016/j.ejmech.2022.115021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9751013/
https://www.ncbi.nlm.nih.gov/pubmed/36549112
http://dx.doi.org/10.1016/j.ejmech.2022.115021

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