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Canagliflozin reverses Th1/Th2 imbalance and promotes podocyte autophagy in rats with membranous nephropathy

Idiopathic membranous nephropathy is the main cause of chronic kidney disease (CKD). Studies have shown sodium–glucose co-transporter 2 (SGLT2) inhibitors significantly delay renal outcomes in patients with CKD, but the exact mechanism remains unknown. In this study, we investigated the mechanism by...

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Detalles Bibliográficos
Autores principales: Lv, Xin, Wang, Jian, Zhang, Li, Shao, Xian, Lin, Yao, Liu, Hongyan, Ma, Guangyang, Li, Jing, Zhou, Saijun, Yu, Pei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9751039/
https://www.ncbi.nlm.nih.gov/pubmed/36531996
http://dx.doi.org/10.3389/fimmu.2022.993869