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The release of osteoclast-stimulating factors on supraphysiological loading by osteoprogenitors coincides with expression of genes associated with inflammation and cytoskeletal arrangement

Supraphysiological loading induced by unstable orthopedic implants initiates osteoclast formation, which results in bone degradation. We aimed to investigate which mechanosensitive cells in the peri-implant environment produce osteoclast-stimulating factors and how the production of these factors is...

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Detalles Bibliográficos
Autores principales: Bratengeier, Cornelia, Bakker, Astrid D., Liszka, Aneta, Schilcher, Jörg, Fahlgren, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9751069/
https://www.ncbi.nlm.nih.gov/pubmed/36517534
http://dx.doi.org/10.1038/s41598-022-25567-7