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Designed Ankyrin Repeat Proteins as a tool box for analyzing p63

The function of the p53 transcription factor family is dependent on several folded domains. In addition to a DNA-binding domain, members of this family contain an oligomerization domain. p63 and p73 also contain a C-terminal Sterile α-motif domain. Inhibition of most transcription factors is difficu...

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Detalles Bibliográficos
Autores principales: Strubel, Alexander, Münick, Philipp, Chaikuad, Apirat, Dreier, Birgit, Schaefer, Jonas, Gebel, Jakob, Osterburg, Christian, Tuppi, Marcel, Schäfer, Birgit, Knapp, Stefan, Plückthun, Andreas, Dötsch, Volker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9751120/
https://www.ncbi.nlm.nih.gov/pubmed/35717504
http://dx.doi.org/10.1038/s41418-022-01030-y