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Designed Ankyrin Repeat Proteins as a tool box for analyzing p63
The function of the p53 transcription factor family is dependent on several folded domains. In addition to a DNA-binding domain, members of this family contain an oligomerization domain. p63 and p73 also contain a C-terminal Sterile α-motif domain. Inhibition of most transcription factors is difficu...
Autores principales: | Strubel, Alexander, Münick, Philipp, Chaikuad, Apirat, Dreier, Birgit, Schaefer, Jonas, Gebel, Jakob, Osterburg, Christian, Tuppi, Marcel, Schäfer, Birgit, Knapp, Stefan, Plückthun, Andreas, Dötsch, Volker |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9751120/ https://www.ncbi.nlm.nih.gov/pubmed/35717504 http://dx.doi.org/10.1038/s41418-022-01030-y |
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