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Protective and aggressive bacterial subsets and metabolites modify hepatobiliary inflammation and fibrosis in a murine model of PSC

OBJECTIVE: Conflicting microbiota data exist for primary sclerosing cholangitis (PSC) and experimental models. Goal: define the function of complex resident microbes and their association relevant to PSC patients by studying germ-free (GF) and antibiotic-treated specific pathogen-free (SPF) multidru...

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Detalles Bibliográficos
Autores principales: Awoniyi, Muyiwa, Wang, Jeremy, Ngo, Billy, Meadows, Vik, Tam, Jason, Viswanathan, Amba, Lai, Yunjia, Montgomery, Stephanie, Farmer, Morgan, Kummen, Martin, Thingholm, Louise, Schramm, Christoph, Bang, Corinna, Franke, Andre, Lu, Kun, Zhou, Huiping, Bajaj, Jasmohan S, Hylemon, Phillip B, Ting, Jenny, Popov, Yury V, Hov, Johannes Roksund, Francis, Heather L, Sartor, Ryan Balfour
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9751228/
https://www.ncbi.nlm.nih.gov/pubmed/35705368
http://dx.doi.org/10.1136/gutjnl-2021-326500