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Protective and aggressive bacterial subsets and metabolites modify hepatobiliary inflammation and fibrosis in a murine model of PSC
OBJECTIVE: Conflicting microbiota data exist for primary sclerosing cholangitis (PSC) and experimental models. Goal: define the function of complex resident microbes and their association relevant to PSC patients by studying germ-free (GF) and antibiotic-treated specific pathogen-free (SPF) multidru...
Autores principales: | Awoniyi, Muyiwa, Wang, Jeremy, Ngo, Billy, Meadows, Vik, Tam, Jason, Viswanathan, Amba, Lai, Yunjia, Montgomery, Stephanie, Farmer, Morgan, Kummen, Martin, Thingholm, Louise, Schramm, Christoph, Bang, Corinna, Franke, Andre, Lu, Kun, Zhou, Huiping, Bajaj, Jasmohan S, Hylemon, Phillip B, Ting, Jenny, Popov, Yury V, Hov, Johannes Roksund, Francis, Heather L, Sartor, Ryan Balfour |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9751228/ https://www.ncbi.nlm.nih.gov/pubmed/35705368 http://dx.doi.org/10.1136/gutjnl-2021-326500 |
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