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Epigenetic modulators of B cell fate identified through coupled phenotype-transcriptome analysis

High-throughput methodologies are the cornerstone of screening approaches to identify novel compounds that regulate immune cell function. To identify novel targeted therapeutics to treat immune disorders and haematological malignancies, there is a need to integrate functional cellular information wi...

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Detalles Bibliográficos
Autores principales: Kong, Isabella Y., Trezise, Stephanie, Light, Amanda, Todorovski, Izabela, Arnau, Gisela Mir, Gadipally, Sreeja, Yoannidis, David, Simpson, Kaylene J., Dong, Xueyi, Whitehead, Lachlan, Tempany, Jessica C., Farchione, Anthony J., Sheikh, Amania A., Groom, Joanna R., Rogers, Kelly L., Herold, Marco J., Bryant, Vanessa L., Ritchie, Matthew E., Willis, Simon N., Johnstone, Ricky W., Hodgkin, Philip D., Nutt, Stephen L., Vervoort, Stephin J., Hawkins, Edwin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9751284/
https://www.ncbi.nlm.nih.gov/pubmed/35831623
http://dx.doi.org/10.1038/s41418-022-01037-5