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CryoEM structures of anion exchanger 1 capture multiple states of inward- and outward-facing conformations

Anion exchanger 1 (AE1, band 3) is a major membrane protein of red blood cells and plays a key role in acid-base homeostasis, urine acidification, red blood cell shape regulation, and removal of carbon dioxide during respiration. Though structures of the transmembrane domain (TMD) of three SLC4 tran...

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Detalles Bibliográficos
Autores principales: Zhekova, Hristina R., Jiang, Jiansen, Wang, Weiguang, Tsirulnikov, Kirill, Kayık, Gülru, Khan, Hanif Muhammad, Azimov, Rustam, Abuladze, Natalia, Kao, Liyo, Newman, Debbie, Noskov, Sergei Yu., Tieleman, D. Peter, Hong Zhou, Z., Pushkin, Alexander, Kurtz, Ira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9751308/
https://www.ncbi.nlm.nih.gov/pubmed/36517642
http://dx.doi.org/10.1038/s42003-022-04306-8