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CryoEM structures of anion exchanger 1 capture multiple states of inward- and outward-facing conformations
Anion exchanger 1 (AE1, band 3) is a major membrane protein of red blood cells and plays a key role in acid-base homeostasis, urine acidification, red blood cell shape regulation, and removal of carbon dioxide during respiration. Though structures of the transmembrane domain (TMD) of three SLC4 tran...
Autores principales: | Zhekova, Hristina R., Jiang, Jiansen, Wang, Weiguang, Tsirulnikov, Kirill, Kayık, Gülru, Khan, Hanif Muhammad, Azimov, Rustam, Abuladze, Natalia, Kao, Liyo, Newman, Debbie, Noskov, Sergei Yu., Tieleman, D. Peter, Hong Zhou, Z., Pushkin, Alexander, Kurtz, Ira |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9751308/ https://www.ncbi.nlm.nih.gov/pubmed/36517642 http://dx.doi.org/10.1038/s42003-022-04306-8 |
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