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Deletion of the primase-polymerases encoding gene, located in a mobile element in Thermus thermophilus HB27, leads to loss of function mutation of addAB genes

DNA primase-polymerases (Ppol) have been shown to play active roles in DNA repair and damage tolerance, both in prokaryotes and eukaryotes. The ancestral thermophilic bacterium Thermus thermophilus strain HB27 encodes a Ppol protein among the genes present in mobile element ICETh2, absent in other T...

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Detalles Bibliográficos
Autores principales: Verdú, Carlos, Pérez-Arnaiz, Patricia, Peropadre, Ana, Berenguer, José, Mencía, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9751324/
https://www.ncbi.nlm.nih.gov/pubmed/36532486
http://dx.doi.org/10.3389/fmicb.2022.1005862