Rad5 participates in lesion bypass through its Rev1-binding and ubiquitin ligase domains, but not through its helicase function

DNA Damage Tolerance (DDT) functions to bypass replication-blocking lesions and is divided into two distinct pathways: error-prone Translesion Synthesis (TLS) and error-free Damage Avoidance (DA). Rad5 is a multifunctional protein that is involved in these DDT processes. Saccharomyces cerevisiae Rad...

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Detalles Bibliográficos
Autores principales: Masłowska, Katarzyna H., Pagès, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9751372/
https://www.ncbi.nlm.nih.gov/pubmed/36533078
http://dx.doi.org/10.3389/fmolb.2022.1062027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9751372/
https://www.ncbi.nlm.nih.gov/pubmed/36533078
http://dx.doi.org/10.3389/fmolb.2022.1062027

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