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Rad5 participates in lesion bypass through its Rev1-binding and ubiquitin ligase domains, but not through its helicase function
DNA Damage Tolerance (DDT) functions to bypass replication-blocking lesions and is divided into two distinct pathways: error-prone Translesion Synthesis (TLS) and error-free Damage Avoidance (DA). Rad5 is a multifunctional protein that is involved in these DDT processes. Saccharomyces cerevisiae Rad...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9751372/ https://www.ncbi.nlm.nih.gov/pubmed/36533078 http://dx.doi.org/10.3389/fmolb.2022.1062027 |