Case report: Transfusion independence and abolition of extravascular hemolysis in a PNH patient treated with pegcetacoplan

More than half of patients with paroxysmal nocturnal hemoglobinuria (PNH) treated with complement fraction C5 inhibitors experience residual anemia and hemolysis. This is partly due to the persistent activation of the complement cascade upstream C5, resulting in C3 deposition on PNH erythrocytes and...

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Detalles Bibliográficos
Autores principales: Fattizzo, Bruno, Versino, Francesco, Zaninoni, Anna, Marcello, Anna Paola Maria Luisa, Vercellati, Cristina, Artuso, Silvia, Barcellini, Wilma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9751407/
https://www.ncbi.nlm.nih.gov/pubmed/36532073
http://dx.doi.org/10.3389/fimmu.2022.1060923

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9751407/
https://www.ncbi.nlm.nih.gov/pubmed/36532073
http://dx.doi.org/10.3389/fimmu.2022.1060923

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