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Generation of multicellular tumor spheroids with micro-well array for anticancer drug combination screening based on a valuable biomarker of hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is a highly malignant tumor with a poor prognosis. More than 30% of patients with diagnosed HCC have abnormally high expression of fibroblast growth factor receptor 4 (FGFR4). Currently, clinical trials for a variety of FGFR4-specific inhibitors have started. However,...

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Detalles Bibliográficos
Autores principales: Wang, Qi, Liu, Juan, Yin, Wenzhen, Sun, Dawei, Man, Zhongsong, Jiang, Shangwei, Ran, Xiufeng, Su, Yuxin, Wang, Yunfang, Dong, Jiahong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9751422/
https://www.ncbi.nlm.nih.gov/pubmed/36532586
http://dx.doi.org/10.3389/fbioe.2022.1087656