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Weighted gene co-expression network reveals driver genes contributing to phenotypes of anaplastic thyroid carcinoma and immune checkpoint identification for therapeutic targets

BACKGROUND: Anaplastic thyroid carcinoma (ATC) is a rare but extremely malignant tumor, with a rapid growth rate and early metastasis thus leading to poor survival of patients. The molecular mechanisms underlying these aggressive traits of ATC remain unknown, which impedes the substantial progress i...

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Detalles Bibliográficos
Autores principales: Dong, Xingxing, Yang, Yalong, Hou, Jinxuan, Chen, Weizhen, Yuan, Qianqian, Xu, Gaoran, Liu, Jiuyang, Li, Chengxin, Wu, Gaosong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9751455/
https://www.ncbi.nlm.nih.gov/pubmed/36530988
http://dx.doi.org/10.3389/fonc.2022.1018479