868. In Vitro Activity of Isavuconazole and Other Mould-Active Triazoles Against Aspergillus fumigatus With and Without cyp51 Alterations

BACKGROUND: Azole resistance in Aspergillus fumigatus (AFM) is mainly associated with mutations in cyp51A and its promoter region or its homologue cyp51B. We evaluated the in vitro activity of isavuconazole (ISC), itraconazole (ITC), posaconazole (PSC), and voriconazole (VRC) against 660 AFM collect...

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Detalles Bibliográficos
Autores principales: Pfaller, Michael A, Carvalhaes, Cecilia G, Deshpande, Lalitagauri M, Rhomberg, Paul, Castanheira, Mariana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9751544/
http://dx.doi.org/10.1093/ofid/ofac492.061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9751544/
http://dx.doi.org/10.1093/ofid/ofac492.061

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