622. Population Pharmacokinetic Analysis and Probability of Target Attainment Simulations of Pivmecillinam for the Treatment of Uncomplicated Urinary Tract Infection

BACKGROUND: A population pharmacokinetic model was developed to characterize mecillinam (MEC) pharmacokinetics (PK) and urine exposure after intravenous (IV) administration of MEC or after oral (PO) administration of its prodrug pivmecillinam (PIV) in healthy subjects and patients with renal impairm...

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Detalles Bibliográficos
Autores principales: Santerre Henriksen, Anne Laurence, Lagraauw, Maxime, Prohn, Marita, Lindbom, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9751708/
http://dx.doi.org/10.1093/ofid/ofac492.674

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9751708/
http://dx.doi.org/10.1093/ofid/ofac492.674

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